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Mycophenolate Mofetil

CAT: 0804-HY-B0199-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0199-01Size:100 mg
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Description
Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH) . Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation[1].
CAS Number
128794-94-5
Product Name Alternative
RS 61443; TM-MMF
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Bacterial; Drug Metabolite; Endogenous Metabolite
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mycophenolate-mofetil.html
Concentration
10mM
Purity
99.83
Solubility
1M NaOH : 33.33 mg/mL (ultrasonic; adjust pH to 12 with 1M NaOH) |DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OCCN1CCOCC1)CC/C(C)=C/CC2=C(O)C3=C(COC3=O)C(C)=C2OC
Molecular Formula
C23H31NO7
Molecular Weight
433.49
Precautions
H302, H315, H319, H335
References & Citations
[1]Simmons WD, et al. Preliminary risk-benefit assessment of mycophenolate mofetil in transplant rejection. Drug Saf. 1997;17 (2) :75-92.|[2]Fulton B, et al. Mycophenolate mofetil. A review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in renal transplantation. Drugs. 1996;51 (2) :278-298.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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