GTX-758

• Description:

  GTX-758 is an orally active, nonsteroidal, selective agonist of ERα. GTX-758 plays an important role in castration resistant prostate cancer (CRPC) research[1].

• UNSPSC:

  12352005

• Target:

  Estrogen Receptor/ERR

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Cancer

• Purity:

  99.59

• Smiles:

  O=C(N(C1=CC=C(F)C=C1)C2=CC=C(O)C=C2)C3=CC=C(O)C(F)=C3

• Molecular Formula:

  C19H13F2NO3

• Molecular Weight:

  341.31

• References & Citations:

  [1]M.S. Steiner, et al. 923P - GTX-758, An Oral ERa Agonist, Increases Sex Hormone Binding Globulin, Reduces Free T and Decreases PSA in Patients with Castration Resistant Prostate Cancer. Annals of Oncology Volume 23, Supplement 9, September 2012, Page ix304

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  ERα

• CAS Number:

  [938067-78-8]