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PF-04363467

CAT: 0804-HY-11056Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-11056Size:1 Each
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Description
PF-04363467 is a highly preferring D3R antagonist. PF-04363467 produces dose-dependent changes in the EEG profile of freely moving rats. PF-4363467 attenuates opioid drug-seeking behavior without concomitant D2 side effects. PF-04363467 can be used for the study of addiction, cognitive and mental illness[1].
CAS Number
1010382-72-5
UNSPSC
12352005
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=S(C1=CC=C(C(C)C)C=C1)(NC2=CC=C(C3CN(CC)CCO3)C=C2C)=O
Molecular Formula
C22H30N2O3S
Molecular Weight
402.55
References & Citations
[1]Kiss B, et al. Neuronal dopamine D3 receptors: translational implications for preclinical research and CNS disorders. Biomolecules. 2021 Jan 14;11 (1) :104.|[2]Puryear CB, et al. selective D3-‐receptor antagonist PF-‐04363467. Delta.;2:1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D3 Receptor

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