Propentofylline-d6

CAT: 0804-HY-107203S-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-107203S-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Propentofylline-d6 (HWA 285-d6) is the deuterium labeled Propentofylline. Propentofylline is a xanthine-derivative that inhibits adenosine uptake and blocks phosphodiesterase activity. Propentofylline has neuroprotective, antiproliferative, and anti-inflammatory effects that improve cognition and dementia severity in patients with Alzheimer's disease or vascular dementia[1][2].
CAS Number
[1216516-37-8]
Product Name Alternative
HWA 285-d6
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology; Neurological Disease
Solubility
10 mM in DMSO
Smiles
C(CC)N1C2=C(N(C)C(=O)N(C(C(C(CC(C)=O)([2H])[2H])([2H])[2H])([2H])[2H])C2=O)N=C1
Molecular Formula
C15H16D6N4O3
Molecular Weight
312.40
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Hudlicka O, Komarek J, Wright AJ. The effect of a xanthine derivative, 1- (5' oxohexyl) -3-methyl-7-propylxanthine (HWA 285), on heart performance and regional blood flow in dogs and rabbits. Br J Pharmacol. 1981;72 (4) :723-730. |[3]Sweitzer S, De Leo J. Propentofylline: glial modulation, neuroprotection, and alleviation of chronic pain. Handb Exp Pharmacol. 2011; (200) :235-250.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-107203-01Propentofylline
HY-110225-01Levetiracetam-d6 (ring-d6)
HY-W062109SOlopatadine-d6
HY-139244SNorgestimate-d6
HY-13234SRifaximin-d6
HY-10261S-01Afatinib-d6
HY-B0284S-01Nifedipine-d6
HY-70002S1-01Enzalutamide-d6
HY-16305S-01Maribavir-d6
HY-10917S-01GW2580-d6

Alternative Products

CatalogName
TRC-P768702-10MGPropentofylline-d6
sc-488543Rac 5-Hydroxy propentofylline-d6
M33635-01Propentofylline
sc-476653Propentofylline-d7
sc-488198Rac 5-Hydroxy Propentofylline
D557101Doxofylline-d6 (dimethyl-d6)
TRC-M260801-0.5MGMethoxychlor-d6 (dimethoxy-d6)
TRC-F421101-200MGFlucythrinate D6 (Dimethyl D6)
TRC-B341001-1MGBezafibrate-d6 (dimethyl-d6)
MF-0102454-01Daminozide-d6 (dimethyl-d6)

Popular Products