Products for Research Use Only
RegisterLogin

Propentofylline

CAT: 0804-HY-107203-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-107203-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Propentofylline is a xanthine-derivative that inhibits adenosine uptake and blocks phosphodiesterase activity. Propentofylline has neuroprotective, antiproliferative, and anti-inflammatory effects that improve cognition and dementia severity in patients with Alzheimer's disease or vascular dementia.
CAS Number
55242-55-2
Product Name Alternative
HWA 285
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/propentofylline.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 12.5 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N(C)C(N1CCCCC(C)=O)=O)N=CN2CCC
Molecular Formula
C15H22N4O3
Molecular Weight
306.36
Precautions
H302+H312+H332
References & Citations
[1]Hudlicka O, Komarek J, Wright AJ. The effect of a xanthine derivative, 1- (5' oxohexyl) -3-methyl-7-propylxanthine (HWA 285), on heart performance and regional blood flow in dogs and rabbits. Br J Pharmacol. 1981;72 (4) :723-730. |[2]Sweitzer S, De Leo J. Propentofylline: glial modulation, neuroprotection, and alleviation of chronic pain. Handb Exp Pharmacol. 2011; (200) :235-250.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

Alternative Products

CatalogName
M33635-01Propentofylline
TRC-P768702-10MGPropentofylline-d6
463054Propentofylline-d7
AR-P03072-01Hydroxy Propentofylline
sc-488198Rac 5-Hydroxy Propentofylline

Popular Products