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8-Prenylchrysin

CAT: 0804-HY-107197Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-107197Size:1 Each
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Description
8-prenylchrysin is a C8-prenylated flavonoid. 8-prenylchrysin inhibits P-gp. 8-prenylchrysin can be used for tumor research[1].
CAS Number
34125-75-2
UNSPSC
12352005
Target
P-glycoprotein
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer
Smiles
O=C1C2=C(O)C=C(O)C(C/C=C(C)\C)=C2OC(C3=CC=CC=C3)=C1
Molecular Formula
C20H18O4
Molecular Weight
322.35
References & Citations
[1]de Wet H, et al. Sequence requirements of the ATP-binding site within the C-terminal nucleotide-binding domain of mouse P-glycoprotein: structure-activity relationships for flavonoid binding. Biochemistry. 2001 Aug 28;40 (34) :10382-91.|[2]Wätjen W, et al. Prenylation enhances cytotoxicity of apigenin and liquiritigenin in rat H4IIE hepatoma and C6 glioma cells. Food Chem Toxicol. 2007 Jan;45 (1) :119-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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