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Stacofylline (hydrochloride)

CAT: 0804-HY-106412ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106412ASize:1 Each
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Description
Stacofylline hydrochloride (S 9977), a Xanthine derivative, is a potent AChE inhibitor with an IC50 of 5-50 nM. Stacofylline shows anti-amnesic and promnesic activities[1][2].
CAS Number
138472-18-1
Product Name Alternative
S 9977
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Drug Derivative
Related Pathways
Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C1C2=C(N(C)C(N1C)=O)N=C(CCCN3CCN(CC3)C(N(CC)CC)=O)N2C.Cl
Molecular Formula
C20H34ClN7O3
Molecular Weight
455.98
References & Citations
[1]L E Trudeau, et al. Xanthine derivatives IBMX and S-9977-2 potentiate transmission at an Aplysia central cholinergic synapse. Brain Res. 1992 Jul 17;586 (1) :78-85.|[2]Roger D. Porsolt, et al. Potential cognition-enhancing properties of S 9977 in three moenls of amnesia in the mouse. Drug Development Research. 1992.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
AChE

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