(Rac) -Sezolamide

• Description :

  (Rac) -Sezolamide (MK-927 (free base) ; (Rac) -MK 417 (free base) ) is a carbonic anhydrase inhibitor (CAI) (Ki: 12.0 nM) . (Rac) -Sezolamide has a topical intraocular pressure (IOP) lowering effect. (Rac) -Sezolamide can be used in glaucoma research[1].

• Product Name Alternative :

  MK-927 (free base) ; (Rac) -MK 417 (free base)

• UNSPSC :

  12352005

• Target :

  Carbonic Anhydrase

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Endocrinology

• Smiles :

  O=S(N)(C1=CC(C(CCS2(=O)=O)NCC(C)C)=C2S1)=O

• Molecular Formula :

  C11H18N2O4S3

• Molecular Weight :

  338.47

• References & Citations :

  [1]Sugrue MF, et al. MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor. J Ocul Pharmacol. 1990 Spring;6 (1) :9-22.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [123291-07-6]