(Rac) -Sezolamide

• Description:

  (Rac) -Sezolamide (MK-927 (free base) ; (Rac) -MK 417 (free base) ) is a carbonic anhydrase inhibitor (CAI) (Ki: 12.0 nM) . (Rac) -Sezolamide has a topical intraocular pressure (IOP) lowering effect. (Rac) -Sezolamide can be used in glaucoma research[1].

• Product Name Alternative:

  MK-927 (free base) ; (Rac) -MK 417 (free base)

• UNSPSC:

  12352005

• Target:

  Carbonic Anhydrase

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Endocrinology

• Smiles:

  O=S(N)(C1=CC(C(CCS2(=O)=O)NCC(C)C)=C2S1)=O

• Molecular Formula:

  C11H18N2O4S3

• Molecular Weight:

  338.47

• References & Citations:

  [1]Sugrue MF, et al. MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor. J Ocul Pharmacol. 1990 Spring;6 (1) :9-22.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  123291-07-6