Sezolamide

• Description :

  Sezolamide (MK 417 free base) is a potent topical carbonic anhydrase inhibitor. Sezolamide can be used in studies to reduce intraocular pressure[1].

• Product Name Alternative :

  MK 417 (free base) ; (S) -MK-927 (free base)

• UNSPSC :

  12352005

• Target :

  Carbonic Anhydrase

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Neurological Disease

• Smiles :

  O=S1(C2=C(C=C(S2)S(N)(=O)=O)[C@H](CC1)NCC(C)C)=O

• Molecular Formula :

  C11H18N2O4S3

• Molecular Weight :

  338.47

• References & Citations :

  [1]Gunning FP, et al. Two topical carbonic anhydrase inhibitors sezolamide and dorzolamide in Gelrite vehicle: a multiple-dose efficacy study. Graefes Arch Clin Exp Ophthalmol. 1993 Jul;231 (7) :384-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [123308-22-5]