E 3040

• Description :

  E 3040 is an orally active dual inhibitor of 5-lipoxygenase and thromboxane synthase. E 3040 exhibits anti-inflammatory effect[1].

• UNSPSC :

  12352005

• Target :

  Lipoxygenase; Prostaglandin Receptor

• Related Pathways :

  GPCR/G Protein; Metabolic Enzyme/Protease

• Field of Research :

  Inflammation/Immunology

• Smiles :

  OC1=C(C)C(CC2=CC=CN=C2)=C3N=C(NC)SC3=C1C

• Molecular Formula :

  C16H17N3OS

• Molecular Weight :

  299.39

• References & Citations :

  [1]Oketani K, et al. Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide. Eur J Pharmacol. 2001 Sep 14;427 (2) :159-66.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Isoform :

  5-LOX

• CAS Number :

  [145096-30-6]