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Falnidamol (Standard)

CAT: 0804-HY-10322R-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-10322R-01Size:1 mg
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Description
Falnidamol (Standard) is the analytical standard of Falnidamol. This product is intended for research and analytical applications. Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. Falnidamol displays > 1000-fold lower potency against ErbB2 (IC50=3.4 μM) and a range of other related tyrosine kinases (IC50>10 μM) . Falnidamol is a pyrimido-pyrimidine compound and has anti-cancer activity[1][2].
CAS Number
196612-93-8
Product Name Alternative
BIBX 1382 (Standard)
UNSPSC
12352005
Target
EGFR; Reference Standards
Related Pathways
JAK/STAT Signaling; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
ClC1=CC(NC2=NC=NC3=CN=C(NC(CC4)CCN4C)N=C23)=CC=C1F
Molecular Formula
C18H19ClFN7
Molecular Weight
387.84
References & Citations
[1]Solca FF, et al. Inhibition of epidermal growth factor receptor activity by two pyrimidopyrimidine derivatives. J Pharmacol Exp Ther. 2004 Nov;311 (2) :502-9.|[2]Dittrich Ch, et al. Phase I and pharmacokinetic study of BIBX 1382 BS, an epidermal growth factor receptor (EGFR) inhibitor, given in a continuous daily oral administration. Eur J Cancer. 2002 May;38 (8) :1072-80.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

CatalogName
GTR19178867-01Falnidamol
A11334-100Falnidamol (BIBX 1382) 100mg
A11334-25Falnidamol (BIBX 1382) 25mg
A11334-10Falnidamol (BIBX 1382) 10mg
A11334-5Falnidamol (BIBX 1382) 5mg
A11334-200Falnidamol (BIBX 1382) 200mg
A11334-50Falnidamol (BIBX 1382) 50mg
A11334-2Falnidamol (BIBX 1382) 2mg
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abx098968-01Standard

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