Products for Research Use Only

Falnidamol

CAT: 0013-GTR19178867-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19178867-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Falnidamol (BIBX 1382) is a pyrimido-pyrimidine-based, orally bioavailable small molecule that potently and selectively inhibits EGFR tyrosine kinase (IC50=3 nM) . It exhibits over 1000-fold selectivity against ErbB2 and is used in cancer research for its anti-proliferative effects in both cellular and animal models of EGFR-driven tumors.
CAS Number
196612-93-8
Product Name Alternative
EGFR, Falnidamol, BIBX 1382, BIBX1382, BIBX-1382
Field of Research
Cardiovascular Research, Signal Transduction
Purity
96.46% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.58 mM) ; DMSO:28.8 mg/mL (74.26 mM)
Smiles
CN1CCC (CC1) Nc1ncc2ncnc (Nc3ccc (F) c (Cl) c3) c2n1
Molecular Formula
C18H19ClFN7
Molecular Weight
387.84
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.