Pz 285

• Description :

  Pz 285 is an anti-cancer agent. Pz 285 shows significant inhibitory effect on the viability of MDA-MB-231 breast cancer cells, with an IC50 of 15.0 μM. Pz 285 exhibits remarkable antitumor effects in the mouse tumor xenograft model constructed with highly lung-metastatic MDA-MB-231 LM24 Her2+ breast cancer cells. Pz 285 can be used for the study of breast cancer, especially metastatic breast cancer[1].

• UNSPSC :

  12352005

• Target :

  Others

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Smiles :

  C[C@@]1(OC)OC2=C(/N=C3C(O[C@@](C)(OC)[C@](C)(OC)O4)=C4C(/N=C5C(O[C@@](C)(OC)[C@](C)(OC)O6)=C6/C(N/5)=N/7)=N/3)NC(/N=C8N=C7C9=C\8C(OCCO)=CC=C9OCCO)=C2O[C@@]1(C)OC

• Molecular Formula :

  C42H50N8O16

• Molecular Weight :

  922.89

• References & Citations :

  [1]Kandela IK, et al. Discovery of the Antitumor Effects of a Porphyrazine Diol (Pz 285) in MDA-MB-231 Breast Tumor Xenograft Models in Mice. ACS Med Chem Lett. 2017 Jun 29;8 (7) :705-709.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1400998-20-0]