Pz 285

• Description:

  Pz 285 is an anti-cancer agent. Pz 285 shows significant inhibitory effect on the viability of MDA-MB-231 breast cancer cells, with an IC50 of 15.0 μM. Pz 285 exhibits remarkable antitumor effects in the mouse tumor xenograft model constructed with highly lung-metastatic MDA-MB-231 LM24 Her2+ breast cancer cells. Pz 285 can be used for the study of breast cancer, especially metastatic breast cancer[1].

• UNSPSC:

  12352005

• Target:

  Others

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Smiles:

  C[C@@]1 (OC) OC2=C (/N=C3C (O[C@@] (C) (OC) [C@] (C) (OC) O4) =C4C (/N=C5C (O[C@@] (C) (OC) [C@] (C) (OC) O6) =C6/C (N/5) =N/7) =N/3) NC (/N=C8N=C7C9=C\8C (OCCO) =CC=C9OCCO) =C2O[C@@]1 (C) OC

• Molecular Formula:

  C42H50N8O16

• Molecular Weight:

  922.89

• References & Citations:

  [1]Kandela IK, et al. Discovery of the Antitumor Effects of a Porphyrazine Diol (Pz 285) in MDA-MB-231 Breast Tumor Xenograft Models in Mice. ACS Med Chem Lett. 2017 Jun 29;8 (7) :705-709.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1400998-20-0