SR-18292-d9

• Description :

  SR-18292-d9 is the deuterium labeled SR-18292 (HY-101491) . SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes[1].

• UNSPSC :

  12352005

• Target :

  Autophagy; Isotope-Labeled Compounds; PGC-1α

• Related Pathways :

  Autophagy; Metabolic Enzyme/Protease; Others

• Field of Research :

  Metabolic Disease

• Smiles :

  CC1=CC=C(C=C1)CN(CC(COC2=CC=CC3=C2C=CN3)O)C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]

• Molecular Formula :

  C23H21D9N2O2

• Molecular Weight :

  375.55

• References & Citations :

  [1]Sharabi K, et al. Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 2017 Mar 23;169 (1) :148-160.e15.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported