TP-3654 (Standard)

• Description:

  TP-3654 (Standard) is the analytical standard of TP-3654 (HY-101126) . This product is intended for research and analytical applications. TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively.

• Target:

  Pim; Reference Standards

• Related Pathways:

  JAK/STAT Signaling; Others

• Field of Research:

  Cancer

• Smiles:

  OC(C)(C)[C@H]1CC[C@H](NC2=NN3C(C=C2)=NC=C3C4=CC=CC(C(F)(F)F)=C4)CC1

• Molecular Formula:

  C22H25F3N4O

• Molecular Weight:

  418.46

• References & Citations:

  [1]Foulks JM, et al. A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas. Neoplasia. 2014 May;16 (5) :403-12.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [1361951-15-6]