Hispidin (Standard)

CAT: 0804-HY-100618R-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100618R-01Size:1 mg
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Description
Hispidin (Standard) is the analytical standard of Hispidin. This product is intended for research and analytical applications. Hispidin, a PKC inhibitor and a phenolic compound can be found in Phellinus linteus, has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties[1][2][3][4][5][6][7].
CAS Number
[555-55-5]
UNSPSC
12352005
Target
Akt; Endogenous Metabolite; ERK; Ferroptosis; GSK-3; JAK; JNK; Keap1-Nrf2; p38 MAPK; PKC; Reactive Oxygen Species (ROS) ; Reference Standards; STAT
Related Pathways
Apoptosis; Epigenetics; Immunology/Inflammation; JAK/STAT Signaling; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Others; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Smiles
O=C1C=C(O)C=C(/C=C/C2=CC=C(O)C(O)=C2)O1
Molecular Formula
C13H10O5
Molecular Weight
246.22
References & Citations
[1]Kim DE, et al. The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Exp Cell Res. 2014 Oct 1;327 (2) :264-75.|[2]Wu F, et al. Hispidin Inhibits Ferroptosis Induced by High Glucose via the miR-15b-5p/GLS2 Axis in Pancreatic Beta Cells. Evid Based Complement Alternat Med. 2023 Feb 21;2023:9428241.|[3]Han Y H, et al. Anti-inflammatory effect of hispidin on LPS induced macrophage inflammation through MAPK and JAK1/STAT3 signaling pathways[J]. Applied Biological Chemistry, 2020, 63: 1-9.|[4]Lai MC, et al. Hispidin in the Medicinal Fungus Protects Dopaminergic Neurons from JNK Activation-Regulated Mitochondrial-Dependent Apoptosis in an MPP+-Induced In Vitro Model of Parkinson's Disease. Nutrients. 2023 Jan 20;15 (3) :549.|[5]Kim DE, et al. The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Exp Cell Res. 2014 Oct 1;327 (2) :264-75.|[6]Huang SY, et al. The Protective Effect of Hispidin against Hydrogen Peroxide-Induced Oxidative Stress in ARPE-19 Cells via Nrf2 Signaling Pathway. Biomolecules. 2019 Aug 19;9 (8) :380.|[7]Liu YS, et al. Exploring the Wound Healing Potential of Hispidin. Nutrients. 2024 Sep 19;16 (18) :3161.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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