S3I-1757

• Description:

  S3I-1757 is a STAT3 inhibitor. S3I-1757 inhibits the phosphorylation and dimerization of STAT3. S3I-1757 can be used for the research of STAT3 hyperactive cancers such as melanoma[1].

• UNSPSC:

  12352005

• Target:

  STAT

• Related Pathways:

  JAK/STAT Signaling; Stem Cell/Wnt

• Field of Research:

  Cancer

• Smiles:

  O=C(O)C1=CC(N(CC2=CC=C(C3CCCCC3)C=C2)C(C4=CC=C(OC5=CC=CC=C5)C=C4)=O)=CC=C1O

• Molecular Formula:

  C33H31NO5

• Molecular Weight:

  521.60

• References & Citations:

  [1]Soleimani AH, et al. Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma. Drug Deliv Transl Res. 2017 Aug;7 (4) :571-581.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  STAT3

• CAS Number:

  [1456602-51-9]