Maropitant (citrate)

• Description :

  Maropitant citrate is an orally active NK1 receptor antagonist. Maropitant citrate prevents vomiting and inhibits ulcerative dermatitis[1][2].

• CAS Number :

  [862543-54-2]

• UNSPSC :

  12352005

• Target :

  Neurokinin Receptor

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Smiles :

  CC(C)(C)C1=CC=C(OC)C(CN[C@@H]2[C@H](C(C3=CC=CC=C3)C4=CC=CC=C4)N5CCC2CC5)=C1.O=C(CC(C(O)=O)(O)CC(O)=O)O

• Molecular Formula :

  C38H48N2O8

• Molecular Weight :

  660.80

• References & Citations :

  [1]Hay Kraus BL. Efficacy of orally administered maropitant citrate in preventing vomiting associated with hydromorphone administration in dogs. J Am Vet Med Assoc. 2014 May 15;244 (10) :1164-9.|[2]Williams-Fritze MJ, et al. Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background. J Am Assoc Lab Anim Sci. 2011 Mar;50 (2) :221-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  NK1R