Magnesium citrate

• Description:

  Magnesium citrate (Trimagnesium dicitrate) is an orally active magnesium-containing compound that can cross the blood-brain barrier (BBB) . Magnesium citrate can be used as an intestinal cleanser and is studied for its application in laxatives. Magnesium citrate can also increase the pain threshold and is studied for pain-relief purposes[1][2].

• Product Name Alternative:

  Trimagnesium dicitrate

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Toll-like Receptor (TLR)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/magnesium-citrate.html

• Purity:

  98.0

• Solubility:

  H2O : 4.72 mg/mL (ultrasonic; warming; adjust pH to 2 with HCl; heat to 60°C)

• Smiles:

  C (C (=O) [O-]) C (CC (=O) [O-]) (C (=O) [O-]) O.C (C (=O) [O-]) C (CC (=O) [O-]) (C (=O) [O-]) O.[Mg+2].[Mg+2].[Mg+2]

• Molecular Formula:

  C12H10Mg3O14

• Molecular Weight:

  451.11

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Koc B, et al. Magnesium Citrate Increases Pain Threshold and Reduces TLR4 Concentration in the Brain. Biol Trace Elem Res. 2021;199 (5) :1954-1966. |[2]Hoy SM, et al. Sodium picosulfate/magnesium citrate: a review of its use as a colorectal cleanser. Drugs. 2009;69 (1) :123-36.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  TLR4

• CAS Number:

  3344-18-1