SANT-1 (Standard)

• Description :

  SANT-1 (Standard) is the analytical standard of SANT-1 (HY-100224) . This product is intended for research and analytical applications. SANT-1, a potent Smo antagonist, inhibits Hedgehog signaling. SANT-1 shows IC50s of 20 nM and 30 nM in Shh-LIGHT2 and SmoA1-LIGHT2 assay, respectively[1].

• Target :

  Hedgehog; Reference Standards; Smo

• Related Pathways :

  Others; Stem Cell/Wnt

• Field of Research :

  Cancer

• Smiles :

  CC1=C(/C=N/N2CCN(CC3=CC=CC=C3)CC2)C(C)=NN1C4=CC=CC=C4

• Molecular Formula :

  C23H27N5

• Molecular Weight :

  373.49

• References & Citations :

  [1]Chen JK, et al. Small molecule modulation of Smoothened activity. Proc Natl Acad Sci U S A. 2002 Oct 29;99 (22) :14071-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [304909-07-7]