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Rabbit Polyclonal Antibody to SLC8A1

CAT: 1725-P12693-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P12693-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
In cardiac myocytes, Ca (2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca (2+) concentration during contraction is primarily due to release of Ca (2+) from intracellular stores. However, some Ca (2+) also enters the cell through the sarcolemma (plasma membrane) . During relaxation, Ca (2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca (2+) that entered across the sarcolemma must be extruded from the cell. The Na (+) -Ca (2+) exchanger is the primary mechanism by which the Ca (2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.
Product Name Alternative
NCX1
Swiss Prot
P32418
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human SLC8A1
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
SLC8A1

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