SLC8A1 Polyclonal Antibody

CAT: 0866-RD89682A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD89682A-01Size:60 μL
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Background
In cardiac myocytes, Ca (2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca (2+) concentration during contraction is primarily due to release of Ca (2+) from intracellular stores. However, some Ca (2+) also enters the cell through the sarcolemma (plasma membrane) . During relaxation, Ca (2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca (2+) that entered across the sarcolemma must be extruded from the cell. The Na (+) -Ca (2+) exchanger is the primary mechanism by which the Ca (2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.
Description
This is a SLC8A1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SLC8A1, NCX1
Gene ID
6546
Swiss Prot
P32418
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SLC8A1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:1000-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46kDa/50kDa/54kDa
Observed Molecular Weight
55KDa
Host or Source
Rabbit
Isotype
IgG

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