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Rabbit Polyclonal Antibody to SDHB

CAT: 1725-P12143-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P12143-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Product Name Alternative
IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP
Swiss Prot
P21912
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human SDHB
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
SDHB
Bands Size
32 kDa