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Rabbit Polyclonal Antibody to BFAR

CAT: 1725-P11244-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P11244-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A novel protein, BAR, for bifunctional apoptosis regulator, contains domains that enable it to interact with components of both major apoptosis pathways, where it negatively regulates apoptotic signaling. Like the other anti-apoptosis proteins Bap31 and FLIP, BAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. In addition, BAR contains a domain that also enables it to interact with the mitochondrial Bcl-2 family of proteins. The presence of these various RING, SAM, DED and TM domains suggests that BAR may serve as a scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery.
Product Name Alternative
BAR; RNF47
Swiss Prot
Q9NZS9
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human BFAR
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
BFAR

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