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Rabbit Polyclonal Antibody to RASA4

CAT: 1725-P08672-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P08672-01Size:50 µL
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Description
This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca (2+) . Stimuli that increase intracellular Ca (2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [
Product Name Alternative
GAPL; CAPRI
Swiss Prot
O43374
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human RASA4
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
RASA4