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Rabbit Polyclonal Antibody to DTX2

CAT: 1725-P07250-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P07250-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]) . Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Product Name Alternative
RNF58
Swiss Prot
Q86UW9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human DTX2
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
DTX2

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