Products for Research Use Only
RegisterLogin

Rabbit Polyclonal Antibody to ERBB3

CAT: 1725-P07194-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1725-P07194-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.
Product Name Alternative
HER3; FERLK; LCCS2; VSCN1; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3
Swiss Prot
P21860
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human ERBB3
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
ERBB3

Related Products

CatalogName
P33174-01Rabbit Polyclonal Antibody to Mouse Erbb3 (P1076)
P41543-01Rabbit Polyclonal Antibody to Her3/ErbB3 (Ab-1289)
P40308-01Rabbit Polyclonal Antibody to Her3/ErbB3 (phospho-Tyr1328)
P41544-01Rabbit Polyclonal Antibody to Her3/ErbB3 (Ab-1328)
P10748-01Rabbit Polyclonal Antibody to ERBB2
P12914-01Rabbit Polyclonal Antibody to ERBB4
P31565-01Rabbit Polyclonal Antibody to Mouse Erbb2
P34980-01Rabbit Polyclonal Antibody to Mouse Erbb4
P32888-01Rabbit Polyclonal Antibody to Mouse Erbb2 (P1142)
P32075-01Rabbit Polyclonal Antibody to Phospho-mouse ERBB2 (S999)

Alternative Products

CatalogName
E53P06781ERBB3 Rabbit Polyclonal Antibody
GTR17814065ERBB3 Rabbit Polyclonal Antibody (APC)
GTR17783272ERBB3 Rabbit Polyclonal Antibody (AP)
NBP2-32253Rabbit Polyclonal ErbB3/Her3 Antibody
GTR17750943ERBB3 Rabbit Polyclonal Antibody (PE)
GTR18491060ERBB3 Rabbit Polyclonal Antibody (BF594)
GTR18491059ERBB3 Rabbit Polyclonal Antibody (BF647)
GTR18491056ERBB3 Rabbit Polyclonal Antibody (BF750)
GTR17711588ERBB3 Rabbit Polyclonal Antibody (HRP)
GTR17807228ERBB3 Rabbit Polyclonal Antibody (Cy3)

Popular Products