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Rabbit Polyclonal Antibody to CDKN1B

CAT: 1725-P07187-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P07187-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4) .
Product Name Alternative
KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Swiss Prot
P46527
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human CDKN1B
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
CDKN1B
Bands Size
22 kDa

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