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Rabbit Polyclonal Antibody to CDKN2C

CAT: 1725-P01195-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P01195-01Size:50 µL
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Description
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported
Product Name Alternative
P18; INK4C; p18-INK4C
Swiss Prot
P42773
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human CDKN2C
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
CDKN2C
Bands Size
18 kDa