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Rabbit Polyclonal Antibody to APIP

CAT: 1725-P07034-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P07034-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
APIP is an APAF1 (MIM 602233) -interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.
Product Name Alternative
APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2
Swiss Prot
Q96GX9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human APIP
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
APIP
Bands Size
27 kDa

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