Products for Research Use Only
RegisterLogin

(E) -Cardamonin

CAT: 0804-HY-N1378-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N1378-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(E) -Cardamonin ((E) -Cardamomin) is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM.
CAS Number
19309-14-9
Product Name Alternative
(E) -Cardamomin; (E) -Alpinetin chalcone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; TRP Channel
Type
Natural Products
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Cardamonin.html
Purity
99.84
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=C(C1=C(OC)C=C(O)C=C1O)/C=C/C2=CC=CC=C2
Molecular Formula
C16H14O4
Molecular Weight
270.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang S, et al. Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain. Molecules. 2016 Aug 29;21 (9) . pii: E1145.|[2]Park MK, et al. Novel anti-nociceptive effects of cardamonin via blocking expression of cyclooxygenase-2 andtransglutaminase-2. Pharmacol Biochem Behav. 2014 Mar;118:10-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Cardamonin

Cardamonin is a member of chalcones.

CAS Number19309-14-9
PubChem CID641785
IUPAC Name(E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
Molecular FormulaC16H14O4
Molecular Weight270.28
XLogP3.5
Topological Polar Surface Area66.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count20
Formal Charge0
Complexity346
SMILES
COC1=CC(=CC(=C1C(=O)/C=C/C2=CC=CC=C2)O)O
InChI
InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+
InChIKey
NYSZJNUIVUBQMM-BQYQJAHWSA-N
Chemical Structure
2D Structure
2D structure of Cardamonin
CAS: 19309-14-9
CID: 641785
Formula: C16H14O4
MW: 270.28
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight270.28
XLogP33.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass270.08920892
Monoisotopic Mass270.08920892
Topological Polar Surface Area66.8 Ų
Heavy Atom Count20
Formal Charge0
Complexity346
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-N0279-01Cardamonin
HY-128978(E, E) -RAMB4
HY-Y0248-01(E, ​E) ​-​Farnesol
HY-114770(E, E) -GLL398
HY-W019710-01(E, E) -RGFP966
HY-N0007-01(E, E) -Bisdemethoxycurcumin
HY-131520(E, E, E) -Farnesyl alcohol azide
HY-N12873(E, E, E, ) -10,12,14-Hexadecatrienal
HY-P10922Cathepsin E substrate e
HY-Y0248R-01(E, E) -Farnesol (Standard)

Alternative Products

CatalogName
FC66017-01Cardamonin
GTR19162923-01Cardamonin?

Popular Products