Alloc-Val-Ala-pAB

• Target :

  ADC Linker

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Bioactivity :

  Alloc-Val-Ala-PAB is a cleavable peptide linker employed in the synthesis of antibody-drug conjugates (ADC) . The Val-Ala sequence is specifically cleaved by cathepsin B. The Alloc group remains stable when treated with piperidine and TFA, yet it can be easily removed under mild conditions via palladium-catalyzed allyl transfer.

• Smiles :

  N(C([C@@H](NC([C@@H](NC(OCC=C)=O)[C@@H](C)C)=O)C)=O)C1=CC=C(CO)C=C1

• Molecular Formula :

  C19H27N3O5

• Molecular Weight :

  377.435

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1343407-91-9