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Alloc-Val-Ala-pAB

CAT: 0013-GTR19253441-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19253441-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alloc-Val-Ala-PAB is a cleavable peptide linker employed in the synthesis of antibody-drug conjugates (ADC) . The Val-Ala sequence is specifically cleaved by cathepsin B. The Alloc group remains stable when treated with piperidine and TFA, yet it can be easily removed under mild conditions via palladium-catalyzed allyl transfer.
CAS Number
1343407-91-9
Smiles
N (C ([C@@H] (NC ([C@@H] (NC (OCC=C) =O) [C@@H] (C) C) =O) C) =O) C1=CC=C (CO) C=C1
Molecular Formula
C19H27N3O5
Molecular Weight
377.435
Storage Conditions
-20°C
Notes
For research use only.

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