Alloc-Val-Ala-OH

• CAS Number :

  330970-70-2

• Bioactivity :

  Alloc-Val-Ala-OH (((Allyloxy) carbonyl) -L-valyl-L-alanine) serves as a building block in the synthesis of Tesirine, which is a clinical antibody-drug conjugate (ADC) featuring a pyrrolobenzodiazepine (PBD) dimer payload. The Val-Ala sequence is cleaved specifically by cathepsin B. The Alloc group is stable towards piperidine and TFA, yet can be easily removed under mild conditions via palladium-catalyzed allyl transfer.

• Smiles :

  [C@H](C(N[C@H](C(O)=O)C)=O)(NC(OCC=C)=O)C(C)C

• Molecular Formula :

  C12H20N2O5

• Molecular Weight :

  272.298

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C