Products for Research Use Only

Temporin-SHa

CAT: 0931-TP3904-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-TP3904-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1065010-73-2
Target
Antifungal, Parasite, HIV Protease, Antibacterial
Related Pathways
Proteases/Proteasome, Microbiology/Virology
Bioactivity
Temporin-Sha is an antimicrobial peptide known for its broad-spectrum biological activity. It is effective against Gram-positive bacteria (such as Listeria, MIC= 6.25 μM), Gram-negative bacteria (such as Escherichia coli, MIC= 10 μM), and resistant strains like Methicillin-resistant Staphylococcus aureus. Additionally, Temporin-Sha inhibits Candida albicans (MIC= 25 μM), Saccharomyces cerevisiae (MIC= 12 μM), Leishmania promastigotes and amastigotes (IC50= 9-20 μM), and Trypanosomes (IC50= 17 μM) . It also exhibits antiviral activity against HSV-1 and shows anticancer properties, displaying cytotoxicity towards breast cancer cells MCF-7 and lung cancer cells H460.
Smiles
[C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)N)=O)CC(C)C)=O)CO)=O)=O)[C@H](CC)C)=O)C(C)C)=O)=O)CCSC)=O)CC(C)C)=O)=O)CCCCN)=O)(C(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)CC(C)C
Molecular Formula
C67H109N15O14S
Molecular Weight
1380.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C