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Temporin-GHd

CAT: 0931-TP2654-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2654-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2755770-50-2
Target
Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
Temporin-GHd demonstrates antibacterial properties against Streptococcus mutans with a minimum inhibitory concentration (MIC) of 13.1 μM and a minimum bactericidal concentration (MBC) of 26 μM. It enhances the permeability of the bacterial cell membrane, leading to damage and leakage of cellular components. At elevated concentrations, Temporin-GHd disrupts existing biofilms and can bind to bacterial DNA, thereby hindering DNA migration.
Smiles
[C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)=O)=O)CO)=O)CC(C)C)=O)C)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)NC([C@@H](NC([C@@H](NC([C@H](CC5=CC=CC=C5)N)=O)CC(C)C)=O)CCC(N)=O)=O
Molecular Formula
C76H108N18O16
Molecular Weight
1529.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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