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NNC0165-1273

CAT: 0931-TP3852-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3852-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Neuropeptide Y Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
NNC0165-1273 is a peptide YY (PYY3-36) analogue acting as an intestinal hormone. It shows significantly higher affinity for the Y2 receptor compared to the Y1, Y4, and Y5 receptors. NNC0165-1273 effectively induces anorexia and decreases food intake prompted by nocturnal and ghrelin stimulation through increased satiety. It also inhibits the expression of cFos in NPY/AgRP neurons induced by ghrelin. NNC0165-1273 is applicable in anti-obesity therapy research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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