SR-1277

• Target :

  Casein Kinase

• Related Pathways :

  Stem Cells|||Metabolism

• Bioactivity :

  SR-1277 is a potent, highly selective and ATP-competitive CK1?/? inhibitor with IC50 values of 49 nM and 260 nM, respectively.CK1? plays a crucial role in regulating Wee1 activity at the G2/M cell-cycle interface, and exhibits significant antiproliferative activity against a variety of cancer cells.

• Smiles :

  O=[N+](C1=CC=CC2=C1NC(CNC3=NC(N4CCOCC4)=NC5=C3N=CN5C6=CSC=C6)=N2)[O-]

• Molecular Formula :

  C21H19N9O3S

• Molecular Weight :

  477.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1446715-47-4