SR-1277

• Target:

  Casein Kinase

• Related Pathways:

  Stem Cells|||Metabolism

• Bioactivity:

  SR-1277 is a potent, highly selective and ATP-competitive CK1?/? inhibitor with IC50 values of 49 nM and 260 nM, respectively.CK1? plays a crucial role in regulating Wee1 activity at the G2/M cell-cycle interface, and exhibits significant antiproliferative activity against a variety of cancer cells.

• Smiles:

  O=[N+] (C1=CC=CC2=C1NC (CNC3=NC (N4CCOCC4) =NC5=C3N=CN5C6=CSC=C6) =N2) [O-]

• Molecular Formula:

  C21H19N9O3S

• Molecular Weight:

  477.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1446715-47-4