Products for Research Use Only

SR-1277

CAT: 0931-T38927-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T38927-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1446715-47-4
Target
Casein Kinase
Related Pathways
Stem Cells, Metabolism
Bioactivity
SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor with IC50 values of 49 nM and 260 nM, respectively.CK1δ plays a crucial role in regulating Wee1 activity at the G2/M cell-cycle interface, and exhibits significant antiproliferative activity against a variety of cancer cells.
Smiles
O=[N+](C1=CC=CC2=C1NC(CNC3=NC(N4CCOCC4)=NC5=C3N=CN5C6=CSC=C6)=N2)[O-]
Molecular Formula
C21H19N9O3S
Molecular Weight
477.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C