OPBP-1

CAT: 0931-TP3626-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP3626-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PD-1/PD-L1
Related Pathways
Cell Cycle/Checkpoint|||Immunology/Inflammation|||Apoptosis
Bioactivity
OPBP-1 is a D-peptide developed through phage display screening, molecular docking, and molecular dynamics simulations. It exhibits high stability, strong antitumor activity, and oral bioavailability. OPBP-1 selectively binds to the PD-L1 protein, significantly blocking the interaction between PD-1 and PD-L1, which helps restore and enhance T lymphocyte function while reducing the proportion of myeloid-derived suppressor cells (MDSCs), counteracting tumor-induced immune evasion. OPBP-1 is applicable for research in cancer immunotherapy.
Molecular Formula
C64H92N20O19S
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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