A17 peptide

• Target :

  HSP

• Related Pathways :

  Metabolism|||Cytoskeletal Signaling

• Bioactivity :

  A17 peptide is an Hsp70-targeting peptide. It binds to the ATP-binding domain of Hsp70, specifically inhibiting its chaperone activity. This enhances cellular sensitivity to chemotherapeutic drugs, such as those inducing apoptosis via Cisplatin. A17 peptide is applicable in cancer chemotherapy research, including studies on multiple myeloma.

• Smiles :

  C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CCCCN)=O)=O)CCCNC(=N)N)(=O)[C@H]3N(C([C@@H](NC([C@H](CC4=CC=C(O)C=C4)NC([C@H](CC5=CC=C(O)C=C5)NC([C@@H](NC([C@@H](NC([C@H](CC6=CC=C(O)C=C6)N)=O)CS)=O)C)=O)=O)=O)CO)=O)CCC3

• Molecular Formula :

  C76H105N19O20S

• Molecular Weight :

  1636.83

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1140483-31-3