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A17 peptide

CAT: 0931-TP3953-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3953-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1140483-31-3
Target
HSP
Related Pathways
Metabolism, Cytoskeletal Signaling
Bioactivity
A17 peptide is an Hsp70-targeting peptide. It binds to the ATP-binding domain of Hsp70, specifically inhibiting its chaperone activity. This enhances cellular sensitivity to chemotherapeutic drugs, such as those inducing apoptosis via Cisplatin. A17 peptide is applicable in cancer chemotherapy research, including studies on multiple myeloma.
Smiles
C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CCCCN)=O)=O)CCCNC(=N)N)(=O)[C@H]3N(C([C@@H](NC([C@H](CC4=CC=C(O)C=C4)NC([C@H](CC5=CC=C(O)C=C5)NC([C@@H](NC([C@@H](NC([C@H](CC6=CC=C(O)C=C6)N)=O)CS)=O)C)=O)=O)=O)CO)=O)CCC3
Molecular Formula
C76H105N19O20S
Molecular Weight
1636.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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