Tat-βsyn-degron

CAT: 0931-TP3532-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-TP3532-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2816095-52-8

Target

Others

Related Pathways

Others

Bioactivity

Tat-βsyn-degron is an α-synuclein (α-synuclein) knockdown peptide that efficiently degrades the α-synuclein protein via the proteasome pathway. It effectively reduces α-synuclein protein levels in primary rat cortical neuron cultures. In Parkinson's mouse toxicity models, Tat-βsyn-degron alleviates neuronal damage and motor dysfunction induced by Parkinsonian toxins.

Smiles

[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(NCC(O)=O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)C(C)C)=O)CC(C)C)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CCCCN)=O)CO)=O)=O)C(C)C)=O

Molecular Formula

C132H237N59O31

Molecular Weight

3146.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Tat-βsyn-degron

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