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VSLRGDTRG acetate

CAT: 0931-TP3245-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3245-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
FAK, ERK, Integrin
Related Pathways
Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, MAPK, Angiogenesis
Bioactivity
VSLRGDTRG acetate is a synthetic peptide of the RGD motif from cadherin17 (CDH17), capable of binding to α2β1 integrin and activating its signaling pathways. It facilitates the high-affinity conformational change of β1 integrin via the RGD motif, enhancing cell adhesion and phosphorylation of FAK and ERK1/2, thereby promoting tumor proliferation and metastasis. VSLRGDTRG acetate is applicable in research on cancers expressing CDH17, such as colon and pancreatic cancers.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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