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VSLRGDTRG

CAT: 0931-TP3241-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3241-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2027476-29-3
Target
Integrin, ERK, FAK
Related Pathways
MAPK, Cytoskeletal Signaling, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
VSLRGDTRG is a synthetic peptide derived from the RGD motif in cadherin17 (CDH17) that binds to the α2β1 integrin, activating its signaling pathways. By promoting high-affinity conformational changes in β1 integrins through the RGD motif, VSLRGDTRG enhances cell adhesion and the phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. This peptide is useful for research on cancers expressing CDH17, such as colorectal and pancreatic cancer.
Smiles
[C@@H](NC([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CO)=O)CC(C)C)=O)(C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(NCC(O)=O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)=O)CCCNC(=N)N
Molecular Formula
C38H69N15O14
Molecular Weight
960.047
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-P10941VSLRGDTRG
HY-P10941A-01VSLRGDTRG (acetate)
GTR19133749-01VSLRGDTRG acetate

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