SjDX5-271

• Target:

  NF-?B|||TLR

• Related Pathways:

  NF-?B|||Immunology/Inflammation

• Bioactivity:

  SjDX5-271 is a 3 kDa peptide that inhibits the TLR4/MyD88/NF-?B signaling pathway. It induces cell polarization, alleviates liver inflammation, and protects mice from liver ischemia-reperfusion injury.

• Smiles:

  C([C@H](CC1=CC=CC=C1)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CCCCN)=O)CC(N)=O)=O)CC(C)C)=O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CO)=O)=O)CO)=O)CO)=O)CCC(N)=O)=O)=O)CCC(N)=O)=O)(=O)N3[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CCC(N)=O)=O)CCC4)CCCNC(=N)N)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCSC)=O)CCC(N)=O)=O)=O)CO)=O)CCC3

• Molecular Formula:

  C137H215N47O49S

• Molecular Weight:

  3336.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2767993-76-8