BIRM 271

• Target:

  LTR|||Leukotriene Receptor|||Phospholipase

• Related Pathways:

  Metabolism|||GPCR/G Protein|||Immunology/Inflammation

• Purity:

  0.9978

• Bioactivity:

  BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. BIRM 271 and BIRM 270 are enantiomers that inhibit the production of leukotriene B4 with IC50 of 40 nM.

• Smiles:

  N([C@H](CC1CCCCC1)C2=CC=CC=N2)C=3OC=4C(N3)=CC(C)=CC4

• Molecular Formula:

  C21H25N3O

• Molecular Weight:

  335.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  149106-77-4