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PKHB1

CAT: 0931-TP2999-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP2999-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1505523-99-8
Target
Reactive Oxygen Species|||Thrombopoietin Receptor
Related Pathways
Metabolism|||Immunology/Inflammation|||NF-?B
Bioactivity
PKHB1 is a thrombospondin-1 peptide mimetic known for its antitumor properties. It induces mitochondrial alterations, ROS generation, intracellular Ca+ accumulation, and calcium-dependent cell death in breast cancer cells. Additionally, PKHB1 promotes immune system activation through immunogenic cell death in breast cancer cells.
Smiles
C([C@@H](C(N[C@H](C(N[C@H](CCCCN)C(O)=O)=O)CCCCN)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](CCCCN)N)=O)CCCNC(=N)N)=O)=O)=O)C(C)C)=O)[C@H](C)C)=O)CCSC)=O)C=3C=4C(NC3)=CC=CC4
Molecular Formula
C68H105N17O12S
Molecular Weight
1384.73
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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