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Cys-PKHB1 TFA

CAT: 0013-GTR19150236-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19150236-01Size:50 mg
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Description
Cys-PKHB1 (Cys-txCD47) TFA is a polypeptide consisting of a cysteine (Cys) residue conjugated with PKHB1, which is a CD47 agonist peptide that mimics the anti-tumor effects of thrombospondin-1 peptides. In breast cancer cells, PKHB1 induces mitochondrial changes, ROS production, intracellular accumulation of Ca+, and calcium-dependent cell death. Furthermore, PKHB1 activates the immune system through immunogenic cell death of breast cancer cells.
Notes
For research use only.

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