KP-6

• Target :

  Wnt/beta-catenin

• Related Pathways :

  Stem Cells|||Cytoskeletal Signaling

• Bioactivity :

  KP-6 is a peptide that acts as an inhibitor of the Wnt/?-catenin signaling pathway. It suppresses TGF-? and disrupts key signals that lead to rapid fibrosis in vivo. KP-6 helps prevent kidney tissue damage and fibrosis, offering the potential to reverse the progression of chronic kidney disease (CKD) .

• Smiles :

  C([C@H](NC([C@H](CC1=CN=CN1)NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]3N(C([C@H](CCC(N)=O)N)=O)CCC3)[C@@H](C)C)=O)C(C)C)=O)[C@@H](C)O)=O)CC(C)C)=O)=O)=O)C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=C(O)C=C5)C(NCC(NCC(N[C@@H](CC=6C=7C(NC6)=CC=CC7)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC8=CN=CN8)C(O)=O)=O)CC(O)=O)=O)C)=O)CC(C)C)=O)C)=O)CCCNC(=N)N)=O)CC(N)=O)=O)C)=O)=O)=O)=O)=O)C)=O)CC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCC4)CC(C)C)=O)CC(O)=O)=O)C=9C=%10C(NC9)=CC=CC%10

• Molecular Formula :

  C159H232N46O44

• Molecular Weight :

  3491.82

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2102414-23-1