MD01-67

• Target :

  Neurotensin Receptor

• Related Pathways :

  GPCR/G Protein

• Bioactivity :

  MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain.

• Smiles :

  [C@H](CC1=CC=C(O)C=C1)(C(N[C@@H](CC2CCCC2)C(O)=O)=O)NC(=O)[C@H]3NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC=CC3

• Molecular Formula :

  C37H58N8O8

• Molecular Weight :

  742.91

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2468971-42-6