YS-67

• Target:

  EGFR|||Akt|||Apoptosis

• Related Pathways:

  JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Apoptosis|||PI3K/Akt/mTOR signaling

• Purity:

  0.9888

• Bioactivity:

  YS-67 is an orally available, selective and potent EGFR inhibitor with antitumor activity, inhibits p-EGFR and p-AKT, and inhibits the proliferation of A549, PC-9, and A431 cells.YS-67 blocks cell cycle progression and induces apoptosis in the G0/G1 phase, and can be used in the study of non-small-cell lung cancer.

• Smiles:

  N=1C=NC(=C2C=C(OCCCN3CCOCC3)C(OC)=CC12)C=4C=5C=CC=CC5N(C4C=6C=CC=CC6)CC

• Molecular Formula:

  C32H34N4O3

• Molecular Weight:

  522.64

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2761327-15-3